About Uncharacterized protein C7orf33
Uncharacterized protein C7orf33 (C7orf33) is a protein
from Homo sapiens identified by UniProt accession
Q8WU49, 177 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Uncharacterized protein C7orf33 |
| UniProt accession | Q8WU49 |
| Gene | C7orf33 |
| Organism | Homo sapiens |
| Length | 177 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- Crohn's disease · score 0.33
- sclerosing cholangitis · score 0.27
- ulcerative colitis · score 0.27
- ankylosing spondylitis · score 0.27
- psoriasis · score 0.27
- inflammatory bowel disease · score 0.25
- mean corpuscular hemoglobin concentration · score 0.07
- mean corpuscular volume · score 0.06
- diffuse plaque measurement · score 0.06
- peptic ulcer disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q8WU49-F1 | alphafold | PREDICTED | 32.15 | — |
Amino-acid sequence (177 residues)
MQVEVQSLSL EECPWRLPGP QCECEALLPS GARRRIDLRL SGRAVAVWVH VRGGPGQFNL SYATGRHKKP NPHQNMNRGM EFIAPVSAPT KSGAPWHFLS QGPTDAQRAV RIRPGTRMGL SSDPVVGTLS SSYLDLLTLS YKPGRTVTSS YLNVRGHEVR KLQNSVEATR ISRTDSS
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