About Protein FAM216A
Protein FAM216A (FAM216A) is a protein
from Homo sapiens identified by UniProt accession
Q8WUB2, 273 residues long.
MolForge cross-references it against 0 known binders and
124 disease associations.
Target properties
| Protein name | Protein FAM216A |
|---|
| UniProt accession | Q8WUB2 |
|---|
| Gene | FAM216A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 273 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (124)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.12
- hemoglobin measurement · score 0.10
- early-onset non-syndromic cataract · score 0.10
- body fat percentage · score 0.10
- isolated ectopia lentis · score 0.08
- body mass index · score 0.08
- red blood cell density measurement · score 0.08
- hereditary hyperferritinemia with congenital cataracts · score 0.08
- Total congenital cataract · score 0.08
- Posterior polar cataract · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WUB2-F1 | alphafold | PREDICTED | 54.44 | — |
Amino-acid sequence (273 residues)
MLGQLLPHTA RGLGAAEMPG QGPGSDWTER SSSAEPPAVA GTEGGGGGSA GYSCYQNSKG SDRIKDGYKV NSHIAKLQEL WKTPQNQTIH LSKSMMEASF FKHPDLTTGQ KRYLCSIAKI YNANYLKMLM KRQYMHVLQH SSQKPGVLTH HRSRLSSRYS QKQHYPCTTW RHQLEREDSG SSDIAAASAP EMLIQHSLWR PVRNKEGIKT GYASKTRCKS LKIFRRPRKL FMQTVSSDDS ESHMSEEKKE EDLLNNFMQS MSIEEQGEHL MLT
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