About Cholinephosphotransferase 1
Cholinephosphotransferase 1 (CHPT1) is a protein
from Homo sapiens identified by UniProt accession
Q8WUD6, 406 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Cholinephosphotransferase 1 |
|---|
| UniProt accession | Q8WUD6 |
|---|
| Gene | CHPT1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 406 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.41
- N-acylethanolamine-hydrolyzing acid amidase measurement · score 0.26
- vitamin C measurement · score 0.25
- breast adenocarcinoma · score 0.18
- habitual abortion · score 0.15
- response to radiation · score 0.08
- Hematochezia · score 0.08
- cathepsin D measurement · score 0.06
- osteoarthritis, knee · score 0.05
- body height · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WUD6-F1 | alphafold | PREDICTED | 90.90 | — |
Amino-acid sequence (406 residues)
MAAGAGAGSA PRWLRALSEP LSAAQLRRLE EHRYSAAGVS LLEPPLQLYW TWLLQWIPLW MAPNSITLLG LAVNVVTTLV LISYCPTATE EAPYWTYLLC ALGLFIYQSL DAIDGKQARR TNSCSPLGEL FDHGCDSLST VFMAVGASIA ARLGTYPDWF FFCSFIGMFV FYCAHWQTYV SGMLRFGKVD VTEIQIALVI VFVLSAFGGA TMWDYTIPIL EIKLKILPVL GFLGGVIFSC SNYFHVILHG GVGKNGSTIA GTSVLSPGLH IGLIIILAIM IYKKSATDVF EKHPCLYILM FGCVFAKVSQ KLVVAHMTKS ELYLQDTVFL GPGLLFLDQY FNNFIDEYVV LWMAMVISSF DMVIYFSALC LQISRHLHLN IFKTACHQAP EQVQVLSSKS HQNNMD
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