Cancer/testis antigen 55 (CT55)

About Cancer/testis antigen 55

Cancer/testis antigen 55 (CT55) is a protein from Homo sapiens identified by UniProt accession Q8WUE5, 264 residues long. MolForge cross-references it against 0 known binders and 113 disease associations.

Target properties

Protein name	Cancer/testis antigen 55
UniProt accession	Q8WUE5
Gene	CT55
Organism	Homo sapiens
Length	264 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (113)

Diseases linked to this target (Open Targets).

male infertility with azoospermia or oligozoospermia due to single gene mutation · score 0.38
azoospermia · score 0.09
male infertility with teratozoospermia due to single gene mutation · score 0.08
multiple myeloma · score 0.08
partial chromosome Y deletion · score 0.07
spermatogenic failure 65 · score 0.06
spermatogenic failure 56 · score 0.06
congenital bilateral absence of vas deferens · score 0.06
spermatogenic failure, X-linked, 3 · score 0.06
spermatogenic failure 72 · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WUE5-F1	alphafold	PREDICTED	75.28	—

Amino-acid sequence (264 residues)

MLRLLRLALA FYGRTADPAE RQGPQQQGLP QGDTQLTTVQ GVVTSFCGDY GMIDESIYFS SDVVTGNVPL KVGQKVNVVV EEDKPHYGLR AIKVDVVPRH LYGAGPSDSG TRVLIGCVTS INEDNIYISN SIYFSIAIVS EDFVPYKGDL LEVEYSTEPG ISNIKATSVK PIRCIHTEEV CITSVHGRNG VIDYTIFFTL DSVKLPDGYV PQVDDIVNVV MVESIQFCFI WRAISITPVH KSSSGFQDDG GLGRPKRERR SQSI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards