About Solute carrier family 22 member 17
Solute carrier family 22 member 17 (SLC22A17) is a protein
from Homo sapiens identified by UniProt accession
Q8WUG5, 649 residues long.
MolForge cross-references it against 0 known binders and
105 disease associations.
Target properties
| Protein name | Solute carrier family 22 member 17 |
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| UniProt accession | Q8WUG5 |
|---|
| Gene | SLC22A17 |
|---|
| Organism | Homo sapiens |
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| Length | 649 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (105)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.12
- chronic lymphocytic leukemia · score 0.09
- neoplasm · score 0.08
- Gollop-Wolfgang complex · score 0.05
- cancer · score 0.05
- tibia, hypoplasia or aplasia of, with polydactyly · score 0.04
- Blount disease · score 0.04
- esophageal squamous cell carcinoma · score 0.04
- acheiropody · score 0.04
- Eiken syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WUG5-F1 | alphafold | PREDICTED | 70.79 | — |
Amino-acid sequence (649 residues)
MAPRVATGTP EPNGGGGGKI DNTVEITPTS NGQVGTLGDA VPTEQLQGER EREREGEGDA GGDGLGSSLS LAVPPGPLSF EALLAQVGAL GGGQQLQLGL CCLPVLFVAL GMASDPIFTL APPLHCHYGA FPPNASGWEQ PPNASGVSVA SAALAASAAS RVATSTDPSC SGFAPPDFNH CLKDWDYNGL PVLTTNAIGQ WDLVCDLGWQ VILEQILFIL GFASGYLFLG YPADRFGRRG IVLLTLGLVG PCGVGGAAAG SSTGVMALRF LLGFLLAGVD LGVYLMRLEL CDPTQRLRVA LAGELVGVGG HFLFLGLALV SKDWRFLQRM ITAPCILFLF YGWPGLFLES ARWLIVKRQI EEAQSVLRIL AERNRPHGQM LGEEAQEALQ DLENTCPLPA TSSFSFASLL NYRNIWKNLL ILGFTNFIAH AIRHCYQPVG GGGSPSDFYL CSLLASGTAA LACVFLGVTV DRFGRRGILL LSMTLTGIAS LVLLGLWDCE HPIFPTVWAQ QGNPNRDLNE AAITTFSVLG LFSSQAAAIL STLLAAEVIP TTVRGRGLGL IMALGALGGL SGPAQRLHMG HGAFLQHVVL AACALLCILS IMLLPETKRK LLPEVLRDGE LCRRPSLLRQ PPPTRCDHVP LLATPNPAL
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