About Solute carrier family 25 member 43
Solute carrier family 25 member 43 (SLC25A43) is a protein
from Homo sapiens identified by UniProt accession
Q8WUT9, 341 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Solute carrier family 25 member 43 |
|---|
| UniProt accession | Q8WUT9 |
|---|
| Gene | SLC25A43 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 341 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- neoplasm · score 0.04
- breast cancer · score 0.03
- basal cell carcinoma · score 0.03
- cancer · score 0.02
- glioblastoma multiforme · score 0.02
- astrocytoma · score 0.02
- ependymoma · score 0.01
- tuberculosis · score 0.01
- ovarian carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WUT9-F1 | alphafold | PREDICTED | 88.90 | — |
Amino-acid sequence (341 residues)
MATWRRDGRL TGGQRLLCAG LAGTLSLSLT APLELATVLA QVGVVRGHAR GPWATGHRVW RAEGLRALWK GNAVACLRLF PCSAVQLAAY RKFVVLFTDD LGHISQWSSI MAGSLAGMVS TIVTYPTDLI KTRLIMQNIL EPSYRGLLHA FSTIYQQEGF LALYRGVSLT VVGALPFSAG SLLVYMNLEK IWNGPRDQFS LPQNFANVCL AAAVTQTLSF PFETVKRKMQ AQSPYLPHSG GVDVHFSGAV DCFRQIVKAQ GVLGLWNGLT ANLLKIVPYF GIMFSTFEFC KRICLYQNGY ILSPLSYKLT PGVDQSLQPQ ELRELKKFFK TRKPKPKKPT L
Explore Solute carrier family 25 member 43 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets