Protein LTO1 homolog (LTO1)

About Protein LTO1 homolog

Protein LTO1 homolog (LTO1) is a protein from Homo sapiens identified by UniProt accession Q8WV07, 137 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

Target properties

Protein name	Protein LTO1 homolog
UniProt accession	Q8WV07
Gene	LTO1
Organism	Homo sapiens
Length	137 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (95)

Diseases linked to this target (Open Targets).

monocyte count · score 0.31
neutrophil count · score 0.27
appendicular lean mass · score 0.26
body fat distribution · score 0.26
leukocyte count · score 0.26
myeloid white cell count · score 0.24
platelet count · score 0.22
sex hormone-binding globulin measurement · score 0.21
urate measurement · score 0.21
hip circumference · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WV07-F1	alphafold	PREDICTED	84.53	—

Amino-acid sequence (137 residues)

MAGSQDIFDA IVMADERFHG EGYREGYEEG SSLGVMEGRQ HGTLHGAKIG SEIGCYQGFA FAWKCLLHSC TTEKDSRKMK VLESLIGMIQ KFPYDDPTYD KLHEDLDKIR GKFKQFCSLL NVQPDFKISA EGSGLSF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards