About E3 ubiquitin-protein ligase TRIM41
E3 ubiquitin-protein ligase TRIM41 (TRIM41) is a protein
from Homo sapiens identified by UniProt accession
Q8WV44, 630 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | E3 ubiquitin-protein ligase TRIM41 |
|---|
| UniProt accession | Q8WV44 |
|---|
| Gene | TRIM41 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 630 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- IGF-1 measurement · score 0.26
- hair colour measurement · score 0.26
- insulin like growth factor measurement · score 0.26
- alkaline phosphatase measurement · score 0.26
- BMI-adjusted waist-hip ratio · score 0.22
- BMI-adjusted waist circumference · score 0.19
- clear cell renal carcinoma · score 0.18
- age at menarche · score 0.18
- waist-hip ratio · score 0.14
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WV44-F1 | alphafold | PREDICTED | 72.73 | — |
Amino-acid sequence (630 residues)
MAAVAMTPNP VQTLQEEAVC AICLDYFTDP VSIGCGHNFC RVCVTQLWGG EDEEDRDELD REEEEEDGEE EEVEAVGAGA GWDTPMRDED YEGDMEEEVE EEEEGVFWTS GMSRSSWDNM DYVWEEEDEE EDLDYYLGDM EEEDLRGEDE EDEEEVLEEV EEEDLDPVTP LPPPPAPRRC FTCPQCRKSF PRRSFRPNLQ LANMVQVIRQ MHPTPGRGSR VTDQGICPKH QEALKLFCEV DEEAICVVCR ESRSHKQHSV VPLEEVVQEY KAKLQGHVEP LRKHLEAVQK MKAKEERRVT ELKSQMKSEL AAVASEFGRL TRFLAEEQAG LERRLREMHE AQLGRAGAAA SRLAEQAAQL SRLLAEAQER SQQGGLRLLQ DIKETFNRCE EVQLQPPEVW SPDPCQPHSH DFLTDAIVRK MSRMFCQAAR VDLTLDPDTA HPALMLSPDR RGVRLAERRQ EVADHPKRFS ADCCVLGAQG FRSGRHYWEV EVGGRRGWAV GAARESTHHK EKVGPGGSSV GSGDASSSRH HHRRRRLHLP QQPLLQREVW CVGTNGKRYQ AQSSTEQTLL SPSEKPRRFG VYLDYEAGRL GFYNAETLAH VHTFSAAFLG ERVFPFFRVL SKGTRIKLCP
Explore E3 ubiquitin-protein ligase TRIM41 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets