Coiled-coil domain-containing protein 107 (CCDC107)

About Coiled-coil domain-containing protein 107

Coiled-coil domain-containing protein 107 (CCDC107) is a protein from Homo sapiens identified by UniProt accession Q8WV48, 283 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 107
UniProt accession	Q8WV48
Gene	CCDC107
Organism	Homo sapiens
Length	283 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

cartilage-hair hypoplasia · score 0.57
anauxetic dysplasia · score 0.56
metaphyseal dysplasia without hypotrichosis · score 0.55
sex hormone-binding globulin measurement · score 0.17
urate measurement · score 0.16
reticulocyte measurement · score 0.03
protein measurement · score 0.02
hepatocellular carcinoma · score 0.01
coronary artery disease · score 0.01
attention deficit hyperactivity disorder · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WV48-F1	alphafold	PREDICTED	60.91	—

Amino-acid sequence (283 residues)

MAGAVSLLGV VGLLLVSALS GVLGDRANPD LRAHPGNAAH PGSGATEPRR RPPLKDQRER TRAGSLPLGA LYTAAVAAFV LYKCLQGKDE TAVLHEEASK QQPLQSEQQL AQLTQQLAQT EQHLNNLMAQ LDPLFERVTT LAGAQQELLN MKLWTIHELL QDSKPDKDME ASEPGEGSGG ESAGGGDKVS ETGTFLISPH TEASRPLPED FCLKEDEEEI GDSQAWEEPT NWSTETWNLA TSWEVGRGLR RRCSQAVAKG PSHSLGWEGG TTAEGRLKQS LFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards