Dephospho-CoA kinase domain-containing protein (DCAKD)

About Dephospho-CoA kinase domain-containing protein

Dephospho-CoA kinase domain-containing protein (DCAKD) is a protein from Homo sapiens identified by UniProt accession Q8WVC6, 231 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Dephospho-CoA kinase domain-containing protein
UniProt accession	Q8WVC6
Gene	DCAKD
Organism	Homo sapiens
Length	231 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

white matter hyperintensity measurement · score 0.30
body height · score 0.25
heel bone mineral density · score 0.24
hypertension · score 0.24
systolic blood pressure · score 0.18
appendicular lean mass · score 0.17
white matter microstructure measurement · score 0.16
multisite chronic pain · score 0.16
insomnia measurement · score 0.16
blood protein measurement · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WVC6-F1	alphafold	PREDICTED	94.62	—

Amino-acid sequence (231 residues)

MFLVGLTGGI ASGKSSVIQV FQQLGCAVID VDVMARHVVQ PGYPAHRRIV EVFGTEVLLE NGDINRKVLG DLIFNQPDRR QLLNAITHPE IRKEMMKETF KYFLRGYRYV ILDIPLLFET KKLLKYMKHT VVVYCDRDTQ LARLMRRNSL NRKDAEARIN AQLPLTDKAR MARHVLDNSG EWSVTKRQVI LLHTELERSL EYLPLRFGVL TGLAAIASLL YLLTHYLLPY A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards