About RING finger protein 141
RING finger protein 141 (RNF141) is a protein
from Homo sapiens identified by UniProt accession
Q8WVD5, 230 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | RING finger protein 141 |
|---|
| UniProt accession | Q8WVD5 |
|---|
| Gene | RNF141 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 230 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.21
- serum albumin measurement · score 0.11
- blood protein measurement · score 0.08
- platelet count · score 0.08
- asthma · score 0.07
- childhood onset asthma · score 0.06
- systolic blood pressure · score 0.06
- neoplasm · score 0.05
- diastolic blood pressure · score 0.05
- erythrocyte count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WVD5-F1 | alphafold | PREDICTED | 83.42 | — |
Amino-acid sequence (230 residues)
MGQQISDQTQ LVINKLPEKV AKHVTLVRES GSLTYEEFLG RVAELNDVTA KVASGQEKHL LFEVQPGSDS SAFWKVVVRV VCTKINKSSG IVEASRIMNL YQFIQLYKDI TSQAAGVLAQ SSTSEEPDEN SSSVTSCQAS LWMGRVKQLT DEEECCICMD GRADLILPCA HSFCQKCIDK WSDRHRNCPI CRLQMTGANE SWVVSDAPTE DDMANYILNM ADEAGQPHRP
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