Transmembrane protein 170A (TMEM170A)

About Transmembrane protein 170A

Transmembrane protein 170A (TMEM170A) is a protein from Homo sapiens identified by UniProt accession Q8WVE7, 144 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	Transmembrane protein 170A
UniProt accession	Q8WVE7
Gene	TMEM170A
Organism	Homo sapiens
Length	144 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (56)

Diseases linked to this target (Open Targets).

platelet crit · score 0.26
leukocyte count · score 0.25
platelet count · score 0.21
cortical thickness · score 0.19
systolic blood pressure · score 0.13
aneurysm · score 0.12
medical procedure · score 0.12
coronary artery disease · score 0.12
chronic obstructive pulmonary disease · score 0.12
smoking status measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WVE7-F1	alphafold	PREDICTED	82.02	—

Amino-acid sequence (144 residues)

MEREGSGGSG GSAGLLQQIL SLKVVPRVGN GTLCPNSTSL CSFPEMWYGV FLWALVSSLF FHVPAGLLAL FTLRHHKYGR FMSVSILLMG IVGPITAGIL TSAAIAGVYR AAGKEMIPFE ALTLGTGQTF CVLVVSFLRI LATL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards