Sperm-associated microtubule inner protein 5 (SPMIP5)

About Sperm-associated microtubule inner protein 5

Sperm-associated microtubule inner protein 5 (SPMIP5) is a protein from Homo sapiens identified by UniProt accession Q8WW14, 234 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Sperm-associated microtubule inner protein 5
UniProt accession	Q8WW14
Gene	SPMIP5
Organism	Homo sapiens
Length	234 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

low density lipoprotein cholesterol measurement · score 0.29
phosphatidylcholine measurement · score 0.27
high density lipoprotein cholesterol measurement · score 0.23
blood protein measurement · score 0.19
apolipoprotein A 1 measurement · score 0.19
aspartate aminotransferase measurement · score 0.16
phospholipid measurement · score 0.13
cardiovascular disease · score 0.11
systolic blood pressure · score 0.10
freckles · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WW14-F1	alphafold	PREDICTED	62.42	—

Amino-acid sequence (234 residues)

MEPSKTFMRN LPITPGYSGF VPFLSCQGMS KEDDMNHCVK TFQEKTQRYK EQLRELCCAV ATAPKLKPVN SEETVLQALH QYNLQYHPLI LECKYVKKPL QEPPIPGWAG YLPRAKVTEF GCGTRYTVMA KNCYKDFLEI TERAKKAHLK PYEEIYGVSS TKTSAPSPKV LQHEELLPKY PDFSIPDGSC PALGRPLRED PKTPLTCGCA QRPSIPCSGK MYLEPLSSAK YAEG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards