DnaJ homolog subfamily A member 4 (DNAJA4)

Homo sapiens — UniProt Q8WW22

Gene: DNAJA4Homo sapiensSwissProt reviewed

About DnaJ homolog subfamily A member 4

DnaJ homolog subfamily A member 4 (DNAJA4) is a protein from Homo sapiens identified by UniProt accession Q8WW22, 397 residues long. MolForge cross-references it against 0 known binders and 85 disease associations.

Target properties

Protein nameDnaJ homolog subfamily A member 4
UniProt accessionQ8WW22
GeneDNAJA4
OrganismHomo sapiens
Length397 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8WW22-F1alphafoldPREDICTED84.42—

Amino-acid sequence (397 residues)

MVKETQYYDI LGVKPSASPE EIKKAYRKLA LKYHPDKNPD EGEKFKLISQ AYEVLSDPKK RDVYDQGGEQ AIKEGGSGSP SFSSPMDIFD MFFGGGGRMA RERRGKNVVH QLSVTLEDLY NGVTKKLALQ KNVICEKCEG VGGKKGSVEK CPLCKGRGMQ IHIQQIGPGM VQQIQTVCIE CKGQGERINP KDRCESCSGA KVIREKKIIE VHVEKGMKDG QKILFHGEGD QEPELEPGDV IIVLDQKDHS VFQRRGHDLI MKMKIQLSEA LCGFKKTIKT LDNRILVITS KAGEVIKHGD LRCVRDEGMP IYKAPLEKGI LIIQFLVIFP EKHWLSLEKL PQLEALLPPR QKVRITDDMD QVELKEFCPN EQNWRQHREA YEEDEDGPQA GVQCQTA

Explore DnaJ homolog subfamily A member 4 with MolForge

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Quick facts

UniProtQ8WW22
GeneDNAJA4
OrganismHomo sapiens
Length397
Binders0
Diseases85
View on UniProt