About SPRY domain-containing protein 4
SPRY domain-containing protein 4 (SPRYD4) is a protein
from Homo sapiens identified by UniProt accession
Q8WW59, 207 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | SPRY domain-containing protein 4 |
|---|
| UniProt accession | Q8WW59 |
|---|
| Gene | SPRYD4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 207 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- amino acid measurement · score 0.26
- serum metabolite measurement · score 0.25
- glutamine measurement · score 0.24
- blood metabolite measurement · score 0.24
- urate measurement · score 0.23
- bilirubin measurement · score 0.20
- C-reactive protein measurement · score 0.20
- serum albumin measurement · score 0.20
- triglyceride measurement · score 0.20
- metabolite measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WW59-F1 | alphafold | PREDICTED | 88.47 | — |
Amino-acid sequence (207 residues)
MALLFARSLR LCRWGAKRLG VASTEAQRGV SFKLEEKTAH SSLALFRDDT GVKYGLVGLE PTKVALNVER FREWAVVLAD TAVTSGRHYW EVTVKRSQQF RIGVADVDMS RDSCIGVDDR SWVFTYAQRK WYTMLANEKA PVEGIGQPEK VGLLLEYEAQ KLSLVDVSQV SVVHTLQTDF RGPVVPAFAL WDGELLTHSG LEVPEGL
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