About Intelectin-1
Intelectin-1 (ITLN1) is a protein
from Homo sapiens identified by UniProt accession
Q8WWA0, 313 residues long.
MolForge cross-references it against 0 known binders and
277 disease associations.
Target properties
| Protein name | Intelectin-1 |
|---|
| UniProt accession | Q8WWA0 |
|---|
| Gene | ITLN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 313 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (277)
Diseases linked to this target (Open Targets).
- inflammatory bowel disease · score 0.30
- Crohn's disease · score 0.29
- ulcerative colitis · score 0.25
- psoriasis · score 0.24
- sclerosing cholangitis · score 0.23
- ankylosing spondylitis · score 0.23
- SLAM family member 7 measurement · score 0.20
- lung adenocarcinoma · score 0.20
- ovarian cancer · score 0.19
- glioblastoma multiforme · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WWA0-F1 | alphafold | PREDICTED | 92.45 | — |
Amino-acid sequence (313 residues)
MNQLSFLLFL IATTRGWSTD EANTYFKEWT CSSSPSLPRS CKEIKDECPS AFDGLYFLRT ENGVIYQTFC DMTSGGGGWT LVASVHENDM RGKCTVGDRW SSQQGSKAVY PEGDGNWANY NTFGSAEAAT SDDYKNPGYY DIQAKDLGIW HVPNKSPMQH WRNSSLLRYR TDTGFLQTLG HNLFGIYQKY PVKYGEGKCW TDNGPVIPVV YDFGDAQKTA SYYSPYGQRE FTAGFVQFRV FNNERAANAL CAGMRVTGCN TEHHCIGGGG YFPEASPQQC GDFSGFDWSG YGTHVGYSSS REITEAAVLL FYR
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