Glycosylated lysosomal membrane protein (GLMP)

About Glycosylated lysosomal membrane protein

Glycosylated lysosomal membrane protein (GLMP) is a protein from Homo sapiens identified by UniProt accession Q8WWB7, 406 residues long. MolForge cross-references it against 0 known binders and 149 disease associations.

Target properties

Protein name	Glycosylated lysosomal membrane protein
UniProt accession	Q8WWB7
Gene	GLMP
Organism	Homo sapiens
Length	406 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (149)

Diseases linked to this target (Open Targets).

basophil count · score 0.09
mean corpuscular hemoglobin concentration · score 0.09
HbA1c measurement · score 0.09
mean corpuscular volume · score 0.08
head and neck squamous cell carcinoma · score 0.07
erythrocyte count · score 0.07
hemoglobin measurement · score 0.07
serum albumin measurement · score 0.07
red blood cell density measurement · score 0.06
hemoglobin A1 measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WWB7-F1	alphafold	PREDICTED	86.36	—

Amino-acid sequence (406 residues)

MRGSVECTWG WGHCAPSPLL LWTLLLFAAP FGLLGEKTRQ VSLEVIPNWL GPLQNLLHIR AVGTNSTLHY VWSSLGPLAV VMVATNTPHS TLSVNWSLLL SPEPDGGLMV LPKDSIQFSS ALVFTRLLEF DSTNVSDTAA KPLGRPYPPY SLADFSWNNI TDSLDPATLS ATFQGHPMND PTRTFANGSL AFRVQAFSRS SRPAQPPRLL HTADTCQLEV ALIGASPRGN RSLFGLEVAT LGQGPDCPSM QEQHSIDDEY APAVFQLDQL LWGSLPSGFA QWRPVAYSQK PGGRESALPC QASPLHPALA YSLPQSPIVR AFFGSQNNFC AFNLTFGAST GPGYWDQHYL SWSMLLGVGF PPVDGLSPLV LGIMAVALGA PGLMLLGGGL VLLLHHKKYS EYQSIN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards