About Calcyphosin-like protein
Calcyphosin-like protein (CAPSL) is a protein
from Homo sapiens identified by UniProt accession
Q8WWF8, 208 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Calcyphosin-like protein |
|---|
| UniProt accession | Q8WWF8 |
|---|
| Gene | CAPSL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- asthma · score 0.30
- type 1 diabetes mellitus · score 0.29
- biliary liver cirrhosis · score 0.27
- primary biliary cirrhosis · score 0.13
- Oral ulcer · score 0.12
- blood protein measurement · score 0.11
- respiratory system disease · score 0.10
- urinary metabolite measurement · score 0.08
- multiple symmetric lipomatosis · score 0.07
- atopic eczema · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WWF8-F1 | alphafold | PREDICTED | 91.34 | — |
Amino-acid sequence (208 residues)
MAGTARHDRE MAIQAKKKLT TATDPIERLR LQCLARGSAG IKGLGRVFRI MDDDNNRTLD FKEFMKGLND YAVVMEKEEV EELFRRFDKD GNGTIDFNEF LLTLRPPMSR ARKEVIMQAF RKLDKTGDGV ITIEDLREVY NAKHHPKYQN GEWSEEQVFR KFLDNFDSPY DKDGLVTPEE FMNYYAGVSA SIDTDVYFII MMRTAWKL
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