About Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (ASZ1) is a protein
from Homo sapiens identified by UniProt accession
Q8WWH4, 475 residues long.
MolForge cross-references it against 0 known binders and
122 disease associations.
Target properties
| Protein name | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 |
|---|
| UniProt accession | Q8WWH4 |
|---|
| Gene | ASZ1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 475 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WWH4-F1 | alphafold | PREDICTED | 67.24 | — |
Amino-acid sequence (475 residues)
MAASALRGLP VAGGGESSES EDDGWEIGYL DRTSQKLKRL LPIEEKKEKF KKAMTIGDVS LVQELLDSGI SVDSNFQYGW TPLMYAASVA NAELVRVLLD RGANASFEKD KQSILITACS AHGSEEQILK CVELLLSRNA DPNVACRRLM TPIMYAARDG HTQVVALLVA HGAEVNTQDE NGYTALTWAA RQGHKNIVLK LLELGANKML QTKDGKMPSE IAKRNKHHEI FNLLSFTLNP LEGKLQQLTK EDTICKILTT DSDREKDHIF SSYTAFGDLE VFLHGLGLEH MTDLLKERDI TLRHLLTMRE DEFTKNGITS KDQQKILAAL KELQVEEIQF GELSEETKLE ISGDEFLNFL LKLNKQCGHL ITAVQNVITE LPVNSQKITL EWASPQNFTS VCEELVNNVE DLSEKVCKLK DLIQKLQNER ENDPTHIQLR EEVSTWNSRI LKRTAITICG FGFLLFICKL TFQRK
Explore Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets