Cytoglobin (CYGB)

About Cytoglobin

Cytoglobin (CYGB) is a protein from Homo sapiens identified by UniProt accession Q8WWM9, 190 residues long. MolForge cross-references it against 0 known binders and 305 disease associations.

Target properties

Protein name	Cytoglobin
UniProt accession	Q8WWM9
Gene	CYGB
Organism	Homo sapiens
Length	190 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (305)

Diseases linked to this target (Open Targets).

retinitis pigmentosa · score 0.52
Retinal dystrophy · score 0.51
genetic disorder · score 0.17
Posterior column ataxia - retinitis pigmentosa · score 0.16
eosinophil count · score 0.15
neoplasm · score 0.10
melanoma · score 0.09
pure red-cell aplasia · score 0.05
renal fibrosis · score 0.05
type 2 diabetes mellitus · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WWM9-F1	alphafold	PREDICTED	87.47	—

Amino-acid sequence (190 residues)

MEKVPGEMEI ERRERSEELS EAERKAVQAM WARLYANCED VGVAILVRFF VNFPSAKQYF SQFKHMEDPL EMERSPQLRK HACRVMGALN TVVENLHDPD KVSSVLALVG KAHALKHKVE PVYFKILSGV ILEVVAEEFA SDFPPETQRA WAKLRGLIYS HVTAAYKEVG WVQQVPNATT PPATLPSSGP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards