Ankyrin repeat and SOCS box protein 5 (ASB5)

About Ankyrin repeat and SOCS box protein 5

Ankyrin repeat and SOCS box protein 5 (ASB5) is a protein from Homo sapiens identified by UniProt accession Q8WWX0, 329 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Ankyrin repeat and SOCS box protein 5
UniProt accession	Q8WWX0
Gene	ASB5
Organism	Homo sapiens
Length	329 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.34
Hallux valgus · score 0.27
electrocardiography · score 0.22
serum albumin measurement · score 0.18
drug use measurement · score 0.16
total blood protein measurement · score 0.15
aspartate aminotransferase measurement · score 0.15
appendicular lean mass · score 0.14
lean body mass · score 0.08
intraocular pressure measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WWX0-F1	alphafold	PREDICTED	86.13	—

Amino-acid sequence (329 residues)

MSVLEENRPF AQQLSNVYFT ILSLFCFKLF VKISLAILSH FYIVKGNRKE AARIAAEFYG VTQGQGSWAD RSPLHEAASQ GRLLALRTLL SQGYNVNAVT LDHVTPLHEA CLGDHVACAR TLLEAGANVN AITIDGVTPL FNACSQGSPS CAELLLEYGA KAQLESCLPS PTHEAASKGH HECLDILISW GIDVDQEIPH LGTPLYVACM SQQFHCIWKL LYAGADVQKG KYWDTPLHAA AQQSSTEIVN LLLEFGADIN AKNTELLRPI DVATSSSMVE RILLQHEATP SSLYQLCRLC IRSYIGKPRL HLIPQLQLPT LLKNFLQYR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards