About Insulin-like growth factor-binding protein-like 1
Insulin-like growth factor-binding protein-like 1 (IGFBPL1) is a protein
from Homo sapiens identified by UniProt accession
Q8WX77, 278 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Insulin-like growth factor-binding protein-like 1 |
|---|
| UniProt accession | Q8WX77 |
|---|
| Gene | IGFBPL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 278 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.42
- smoking status measurement · score 0.23
- gut microbiome measurement · score 0.19
- smoking behavior · score 0.19
- longevity · score 0.18
- Dental crowding · score 0.10
- lymphocyte count · score 0.08
- platelet count · score 0.08
- lymphocyte percentage of leukocytes · score 0.08
- leukocyte count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WX77-F1 | alphafold | PREDICTED | 85.07 | — |
Amino-acid sequence (278 residues)
MPRLSLLLPL LLLLLLPLLP PLSPSLGIRD VGGRRPKCGP CRPEGCPAPA PCPAPGISAL DECGCCARCL GAEGASCGGR AGGRCGPGLV CASQAAGAAP EGTGLCVCAQ RGTVCGSDGR SYPSVCALRL RARHTPRAHP GHLHKARDGP CEFAPVVVVP PRSVHNVTGA QVGLSCEVRA VPTPVITWRK VTKSPEGTQA LEELPGDHVN IAVQVRGGPS DHEATAWILI NPLRKEDEGV YQCHAANMVG EAESHSTVTV LDLSKYRSFH FPAPDDRM
Explore Insulin-like growth factor-binding protein-like 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets