About Forkhead box protein D4-like 4
Forkhead box protein D4-like 4 (FOXD4L4) is a protein
from Homo sapiens identified by UniProt accession
Q8WXT5, 416 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Forkhead box protein D4-like 4 |
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| UniProt accession | Q8WXT5 |
|---|
| Gene | FOXD4L4 |
|---|
| Organism | Homo sapiens |
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| Length | 416 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- Isolated anophthalmia - microphthalmia · score 0.05
- Microphthalmia - ankyloblepharon - intellectual disability · score 0.05
- nanophthalmia · score 0.04
- microphthalmia · score 0.04
- nanophthalmos 2 · score 0.04
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WXT5-F1 | alphafold | PREDICTED | 56.58 | — |
Amino-acid sequence (416 residues)
MNLPRAERPR STPQRSLRDS DGEDGKIDVL GEEEDEDEVE DEEEEARQQF LEQSLQPGLQ VARWGGVALP REHIEGGGGP SDPSEFGTKF RAPPRSAAAS EDARQPAKPP YSYIALITMA ILQNPHKRLT LSGICAFISG RFPYYRRKFP AWQNSIRHNL SLNDCFVKIP REPGHPGKGN YWSLDPASQD MFDNGSFLRR RKRFKRHQLT PGAHLPHPFP LPAAHAALHN PHPGPLLGAP APPQPVPGAY PNTAPGRRPY ALLHPHPLRY LLLSARVYAG APKKAEGADL ATPAPFPCCS PHLVLSLGRR ARVWRRHREA DASLSALRVL CKGSGERVQG LRRVCPRPRG ATATCSSDHQ ACCIPKPLPL CCKCPPPLLL GQFCSNSSSI RRTAPTAALP PRARCWAGTC RPRRRC
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