About Transmembrane protein 234
Transmembrane protein 234 (TMEM234) is a protein
from Homo sapiens identified by UniProt accession
Q8WY98, 164 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Transmembrane protein 234 |
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| UniProt accession | Q8WY98 |
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| Gene | TMEM234 |
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| Organism | Homo sapiens |
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| Length | 164 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- immune deficiency, familial variable · score 0.05
- hyper-IgM syndrome type 3 · score 0.04
- Hodgkins lymphoma · score 0.04
- classic Hodgkin lymphoma · score 0.04
- hyper-IgM syndrome type 2 · score 0.04
- multiple myeloma · score 0.04
- hyper-IgM syndrome type 5 · score 0.04
- immunodeficiency, common variable, 14 · score 0.03
- Waldenstrom macroglobulinemia · score 0.03
- immunodeficiency, common variable, 7 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WY98-F1 | alphafold | PREDICTED | 84.56 | — |
Amino-acid sequence (164 residues)
MAASLGQVLA LVLVAALWGG TQPLLKRASA GLQRVHEPTW AQQLLQEMKT LFLNTEYLMP FLLNQCGSLL YYLTLASTDL TLAVPICNSL AIIFTLIVGK ALGEDIGGKR AVAGMVLTVI GISLCITSSV PWTAELQLHG KGQLQTLSQK CKREASGTQS ERFG
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