About Cysteine/serine-rich nuclear protein 3
Cysteine/serine-rich nuclear protein 3 (CSRNP3) is a protein
from Homo sapiens identified by UniProt accession
Q8WYN3, 585 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Cysteine/serine-rich nuclear protein 3 |
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| UniProt accession | Q8WYN3 |
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| Gene | CSRNP3 |
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| Organism | Homo sapiens |
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| Length | 585 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (66)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- self reported educational attainment · score 0.43
- cognitive function measurement · score 0.32
- risky sexual behaviour measurement · score 0.29
- Abnormal urine sodium concentration · score 0.29
- sodium measurement · score 0.29
- neurofibrillary tangles measurement · score 0.27
- monocyte count · score 0.22
- diet measurement · score 0.21
- alkaline phosphatase measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WYN3-F1 | alphafold | PREDICTED | 59.78 | — |
Amino-acid sequence (585 residues)
MSGILKRKFE EVDGSSPCSS VRESDDEVSS SESADSGDSV NPSTSSHFTP SSILKREKRL RTKNVHFSCV TVYYFTRRQG FTSVPSQGGS TLGMSSRHNS VRQYTLGEFA REQERLHREM LREHLREEKL NSLKLKMTKN GTVESEEAST LTLDDISDDD IDLDNTEVDE YFFLQPLPTK KRRALLRASG VKKIDVEEKH ELRAIRLSRE DCGCDCRVFC DPDTCTCSLA GIKCQVDRMS FPCGCTKEGC SNTAGRIEFN PIRVRTHFLH TIMKLELEKN REQQIPTLNG CHSEISAHSS SMGPVAHSVE YSIADSFEIE TEPQAAVLHL QSAEELDCQG EEEEEEEDGS SFCSGVTDSS TQSLAPSESD EEEEEEEEEE EEEDDDDDKG DGFVEGLGTH AEVVPLPSVL CYSDGTAVHE SHAKNASFYA NSSTLYYQID SHIPGTPNQI SENYSERDTV KNGTLSLVPY TMTPEQFVDY ARQAEEAYGA SHYPAANPSV IVCCSSSEND SGVPCNSLYP EHRSNHPQVE FHSYLKGPSQ EGFVSALNGD SHISEHPAEN SLSLAEKSIL HEECIKSPVV ETVPV
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