About Transmembrane protein 190
Transmembrane protein 190 (TMEM190) is a protein
from Homo sapiens identified by UniProt accession
Q8WZ59, 177 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Transmembrane protein 190 |
|---|
| UniProt accession | Q8WZ59 |
|---|
| Gene | TMEM190 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 177 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- white matter microstructure measurement · score 0.21
- blood protein measurement · score 0.17
- sitting height measurement · score 0.06
- smoking status measurement · score 0.04
- vital capacity · score 0.02
- nasopharyngeal neoplasm · score 0.01
- gonorrhea · score 0.01
- squamous cell carcinoma · score 0.00
- non-small cell lung carcinoma · score 0.00
- stomach neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WZ59-F1 | alphafold | PREDICTED | 64.49 | — |
Amino-acid sequence (177 residues)
MLGCGIPALG LLLLLQGSAD GNGIQGFFYP WSCEGDIWDR ESCGGQAAID SPNLCLRLRC CYRNGVCYHQ RPDENVRRKH MWALVWTCSG LLLLSCSICL FWWAKRRDVL HMPGFLAGPC DMSKSVSLLS KHRGTKKTPS TGSVPVALSK ESRDVEGGTE GEGTEEGEET EGEEEED
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