About Esterase OVCA2
Esterase OVCA2 (OVCA2) is a protein
from Homo sapiens identified by UniProt accession
Q8WZ82, 227 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Esterase OVCA2 |
|---|
| UniProt accession | Q8WZ82 |
|---|
| Gene | OVCA2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 227 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (63)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.09
- bone quantitative ultrasound measurement · score 0.08
- leukocyte count · score 0.08
- body fat percentage · score 0.08
- body mass index · score 0.08
- lean body mass · score 0.08
- cortical thickness · score 0.08
- fat body mass · score 0.07
- neutrophil count · score 0.07
- BMI-adjusted waist-hip ratio · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8WZ82-F1 | alphafold | PREDICTED | 90.83 | — |
Amino-acid sequence (227 residues)
MAAQRPLRVL CLAGFRQSER GFREKTGALR KALRGRAELV CLSGPHPVPD PPGPEGARSD FGSCPPEEQP RGWWFSEQEA DVFSALEEPA VCRGLEESLG MVAQALNRLG PFDGLLGFSQ GAALAALVCA LGQAGDPRFP LPRFILLVSG FCPRGIGFKE SILQRPLSLP SLHVFGDTDK VIPSQESVQL ASQFPGAITL THSGGHFIPA AAPQRQAYLK FLDQFAE
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