Alpha-2,8-sialyltransferase 8B (ST8SIA2)

About Alpha-2,8-sialyltransferase 8B

Alpha-2,8-sialyltransferase 8B (ST8SIA2) is a protein from Homo sapiens identified by UniProt accession Q92186, 375 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.

Target properties

Protein name	Alpha-2,8-sialyltransferase 8B
UniProt accession	Q92186
Gene	ST8SIA2
Organism	Homo sapiens
Length	375 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92186-F1	alphafold	PREDICTED	84.78	—

Amino-acid sequence (375 residues)

MQLQFRSWML AALTLLVVFL IFADISEIEE EIGNSGGRGT IRSAVNSLHS KSNRAEVVIN GSSSPAVVDR SNESIKHNIQ PASSKWRHNQ TLSLRIRKQI LKFLDAEKDI SVLKGTLKPG DIIHYIFDRD STMNVSQNLY ELLPRTSPLK NKHFGTCAIV GNSGVLLNSG CGQEIDAHSF VIRCNLAPVQ EYARDVGLKT DLVTMNPSVI QRAFEDLVNA TWREKLLQRL HSLNGSILWI PAFMARGGKE RVEWVNELIL KHHVNVRTAY PSLRLLHAVR GYWLTNKVHI KRPTTGLLMY TLATRFCKQI YLYGFWPFPL DQNQNPVKYH YYDSLKYGYT SQASPHTMPL EFKALKSLHE QGALKLTVGQ CDGAT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards