About Protein FAM3C
Protein FAM3C (FAM3C) is a protein
from Homo sapiens identified by UniProt accession
Q92520, 227 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Protein FAM3C |
|---|
| UniProt accession | Q92520 |
|---|
| Gene | FAM3C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 227 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (118)
Diseases linked to this target (Open Targets).
- bone density · score 0.47
- heel bone mineral density · score 0.44
- bone quantitative ultrasound measurement · score 0.43
- osteoporosis · score 0.37
- radius bone mineral density · score 0.37
- cortical thickness · score 0.35
- BMI-adjusted waist-hip ratio · score 0.33
- spine bone mineral density · score 0.31
- hip bone mineral density · score 0.31
- alkaline phosphatase measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92520-F1 | alphafold | PREDICTED | 91.67 | — |
Amino-acid sequence (227 residues)
MRVAGAAKLV VAVAVFLLTF YVISQVFEIK MDASLGNLFA RSALDTAARS TKPPRYKCGI SKACPEKHFA FKMASGAANV VGPKICLEDN VLMSGVKNNV GRGINVALAN GKTGEVLDTK YFDMWGGDVA PFIEFLKAIQ DGTIVLMGTY DDGATKLNDE ARRLIADLGS TSITNLGFRD NWVFCGGKGI KTKSPFEQHI KNNKDTNKYE GWPEVVEMEG CIPQKQD
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