Ankyrin repeat domain-containing protein 7 (ANKRD7)

About Ankyrin repeat domain-containing protein 7

Ankyrin repeat domain-containing protein 7 (ANKRD7) is a protein from Homo sapiens identified by UniProt accession Q92527, 254 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Ankyrin repeat domain-containing protein 7
UniProt accession	Q92527
Gene	ANKRD7
Organism	Homo sapiens
Length	254 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

urate measurement · score 0.26
heel bone mineral density · score 0.26
gut microbiome measurement · score 0.18
adolescent idiopathic scoliosis · score 0.17
triglyceride measurement · score 0.14
open-angle glaucoma · score 0.05
intraocular pressure measurement · score 0.04
neuroimaging measurement · score 0.03
glaucoma · score 0.03
white matter microstructure measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92527-F1	alphafold	PREDICTED	84.46	—

Amino-acid sequence (254 residues)

MNKLFSFWKR KNETRSQGYN LREKDLKKLH RAASVGDLKK LKEYLQIKKY DVNMQDKKYR TPLHLACANG HTDVVLFLIE QQCKINVRDS ENKSPLIKAV QCQNEDCATI LLNFGADPDL RDIRYNTVLH YAVCGQSLSL VEKLLEYEAD LEAKNKDGYT PLLVAVINNN PKMVKFLLEK GADVNASDNY QRTALILAVS GEPPCLVKLL LQQGVELCYE GIVDSQLRNM FISMVLLHRY PQFTASHGKK KHAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards