About SHC-transforming protein 3
SHC-transforming protein 3 (SHC3) is a protein
from Homo sapiens identified by UniProt accession
Q92529, 594 residues long.
MolForge cross-references it against 0 known binders and
99 disease associations.
Target properties
| Protein name | SHC-transforming protein 3 |
|---|
| UniProt accession | Q92529 |
|---|
| Gene | SHC3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 594 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92529-F1 | alphafold | PREDICTED | 61.29 | — |
Amino-acid sequence (594 residues)
MLPRTKYNRF RNDSVTSVDD LLHSLSVSGG GGKVSAARAT PAAAPYLVSG EALRKAPDDG PGSLGHLLHK VSHLKLSSSG LRGLSSAARE RAGARLSGSC SAPSLAAPDG SAPSAPRAPA MSAARKGRPG DEPLPRPPRG APHASDQVLG PGVTYVVKYL GCIEVLRSMR SLDFSTRTQI TREAISRVCE AVPGAKGAFK KRKPPSKMLS SILGKSNLQF AGMSISLTIS TASLNLRTPD SKQIIANHHM RSISFASGGD PDTTDYVAYV AKDPVNRRAC HILECCDGLA QDVIGSIGQA FELRFKQYLQ CPTKIPALHD RMQSLDEPWT EEEGDGSDHP YYNSIPSKMP PPGGFLDTRL KPRPHAPDTA QFAGKEQTYY QGRHLGDTFG EDWQQTPLRQ GSSDIYSTPE GKLHVAPTGE APTYVNTQQI PPQAWPAAVS SAESSPRKDL FDMKPFEDAL KNQPLGPVLS KAASVECISP VSPRAPDAKM LEELQAETWY QGEMSRKEAE GLLEKDGDFL VRKSTTNPGS FVLTGMHNGQ AKHLLLVDPE GTIRTKDRVF DSISHLINHH LESSLPIVSA GSELCLQQPV ERKQ
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