Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (PIGC)

About Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (PIGC) is a protein from Homo sapiens identified by UniProt accession Q92535, 297 residues long. MolForge cross-references it against 0 known binders and 134 disease associations.

Target properties

Protein name	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
UniProt accession	Q92535
Gene	PIGC
Organism	Homo sapiens
Length	297 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92535-F1	alphafold	PREDICTED	89.05	—

Amino-acid sequence (297 residues)

MYAQPVTNTK EVKWQKVLYE RQPFPDNYVD RRFLEELRKN IHARKYQYWA VVFESSVVIQ QLCSVCVFVV IWWYMDEGLL APHWLLGTGL ASSLIGYVLF DLIDGGEGRK KSGQTRWADL KSALVFITFT YGFSPVLKTL TESVSTDTIY AMSVFMLLGH LIFFDYGANA AIVSSTLSLN MAIFASVCLA SRLPRSLHAF IMVTFAIQIF ALWPMLQKKL KACTPRSYVG VTLLFAFSAV GGLLSISAVG AVLFALLLMS ISCLCPFYLI RLQLFKENIH GPWDEAEIKE DLSRFLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards