RAB6A-GEF complex partner protein 2 (RGP1)

About RAB6A-GEF complex partner protein 2

RAB6A-GEF complex partner protein 2 (RGP1) is a protein from Homo sapiens identified by UniProt accession Q92546, 391 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	RAB6A-GEF complex partner protein 2
UniProt accession	Q92546
Gene	RGP1
Organism	Homo sapiens
Length	391 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92546-F1	alphafold	PREDICTED	85.42	—

Amino-acid sequence (391 residues)

MIEVVAELSR GPVFLAGEAL ECVVTVTNPL PPTATSASSE ALAWASAQIH CQFHASESRV ALPPPDSSQP DVQPDSQTVF LPHRGERGQC ILSTPPKILF CDLRLDPGES KSYSYSEVLP IEGPPSFRGQ SVKYVYKLTI GCQRVNSPIT LLRVPLRVLV LTGLQDVRFP QDEAVAPSSP FLEEDEGGKK DSWLAELAGE RLMAATSCRS LHLYNISDGR GKVGTFGIFK SVYRLGEDVV GTLNLGEGTV ACLQFSVSLQ TEERVQPEYQ RRRGAGGVPS VSHVTHARHQ ESCLHTTRTS FSLPIPLSST PGFCTAIVSL KWRLHFEFVT SREPGLVLLP PVEQPEPTTW TGPEQVPVDT FSWDLPIKVL PTSPTLASYA APGPSTSTIT I

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards