Inositol hexakisphosphate kinase 1 (IP6K1)

About Inositol hexakisphosphate kinase 1

Inositol hexakisphosphate kinase 1 (IP6K1) is a protein from Homo sapiens identified by UniProt accession Q92551, 441 residues long. MolForge cross-references it against 0 known binders and 190 disease associations.

Target properties

Protein name	Inositol hexakisphosphate kinase 1
UniProt accession	Q92551
Gene	IP6K1
Organism	Homo sapiens
Length	441 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92551-F1	alphafold	PREDICTED	74.56	—

Amino-acid sequence (441 residues)

MCVCQTMEVG QYGKNASRAG DRGVLLEPFI HQVGGHSSMM RYDDHTVCKP LISREQRFYE SLPPEMKEFT PEYKGVVSVC FEGDSDGYIN LVAYPYVESE TVEQDDTTER EQPRRKHSRR SLHRSGSGSD HKEEKASLSL ETSESSQEAK SPKVELHSHS EVPFQMLDGN SGLSSEKISH NPWSLRCHKQ QLSRMRSESK DRKLYKFLLL ENVVHHFKYP CVLDLKMGTR QHGDDASAEK AARQMRKCEQ STSATLGVRV CGMQVYQLDT GHYLCRNKYY GRGLSIEGFR NALYQYLHNG LDLRRDLFEP ILSKLRGLKA VLERQASYRF YSSSLLVIYD GKECRAESCL DRRSEMRLKH LDMVLPEVAS SCGPSTSPSN TSPEAGPSSQ PKVDVRMIDF AHSTFKGFRD DPTVHDGPDR GYVFGLENLI SIMEQMRDEN Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards