Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3)

About Phosphatidylinositol 3-kinase regulatory subunit gamma

Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) is a protein from Homo sapiens identified by UniProt accession Q92569, 461 residues long. MolForge cross-references it against 0 known binders and 208 disease associations.

Target properties

Protein name	Phosphatidylinositol 3-kinase regulatory subunit gamma
UniProt accession	Q92569
Gene	PIK3R3
Organism	Homo sapiens
Length	461 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92569-F1	alphafold	PREDICTED	80.64	—

Amino-acid sequence (461 residues)

MYNTVWSMDR DDADWREVMM PYSTELIFYI EMDPPALPPK PPKPMTSAVP NGMKDSSVSL QDAEWYWGDI SREEVNDKLR DMPDGTFLVR DASTKMQGDY TLTLRKGGNN KLIKIYHRDG KYGFSDPLTF NSVVELINHY HHESLAQYNP KLDVKLMYPV SRYQQDQLVK EDNIDAVGKK LQEYHSQYQE KSKEYDRLYE EYTRTSQEIQ MKRTAIEAFN ETIKIFEEQC HTQEQHSKEY IERFRREGNE KEIERIMMNY DKLKSRLGEI HDSKMRLEQD LKNQALDNRE IDKKMNSIKP DLIQLRKIRD QHLVWLNHKG VRQKRLNVWL GIKNEDADEN YFINEEDENL PHYDEKTWFV EDINRVQAED LLYGKPDGAF LIRESSKKGC YACSVVADGE VKHCVIYSTA RGYGFAEPYN LYSSLKELVL HYQQTSLVQH NDSLNVRLAY PVHAQMPSLC R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards