AP-3 complex subunit sigma-1 (AP3S1)

About AP-3 complex subunit sigma-1

AP-3 complex subunit sigma-1 (AP3S1) is a protein from Homo sapiens identified by UniProt accession Q92572, 193 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	AP-3 complex subunit sigma-1
UniProt accession	Q92572
Gene	AP3S1
Organism	Homo sapiens
Length	193 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92572-F1	alphafold	PREDICTED	84.78	—

Amino-acid sequence (193 residues)

MIKAILIFNN HGKPRLSKFY QPYSEDTQQQ IIRETFHLVS KRDENVCNFL EGGLLIGGSD NKLIYRHYAT LYFVFCVDSS ESELGILDLI QVFVETLDKC FENVCELDLI FHVDKVHNIL AEMVMGGMVL ETNMNEIVTQ IDAQNKLEKS EAGLAGAPAR AVSAVKNMNL PEIPRNINIG DISIKVPNLP SFK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards