About PHD finger protein 3
PHD finger protein 3 (PHF3) is a protein
from Homo sapiens identified by UniProt accession
Q92576, 2039 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | PHD finger protein 3 |
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| UniProt accession | Q92576 |
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| Gene | PHF3 |
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| Organism | Homo sapiens |
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| Length | 2039 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92576-F1 | alphafold | PREDICTED | 42.97 | — |
Amino-acid sequence (2039 residues)
MDIVDTFNHL IPTEHLDDAL FLGSNLENEV CEDFSASQNV LEDSLKNMLS DKDPMLGSAS NQFCLPVLDS NDPNFQMPCS TVVGLDDIMD EGVVKESGND TIDEEELILP NRNLRDKVEE NSVRSPRKSP RLMAQEQVRS LRQSTIAKRS NAAPLSNTKK ASGKTVSTAK AGVKQPERSQ VKEEVCMSLK PEYHKENRRC SRNSGQIEVV PEVSVSSSHS SVSSCLEMKD EDGLDSKHKC NNPGEIDVPS HELNCSLLSE TCVTIGEKKN EALMECKAKP VGSPLFKFSD KEEHEQNDSI SGKTGETVVE EMIATRKVEQ DSKETVKLSH EDDHILEDAG SSDISSDAAC TNPNKTENSL VGLPSCVDEV TECNLELKDT MGIADKTENT LERNKIEPLG YCEDAESNRQ LESTEFNKSN LEVVDTSTFG PESNILENAI CDVPDQNSKQ LNAIESTKIE SHETANLQDD RNSQSSSVSY LESKSVKSKH TKPVIHSKQN MTTDAPKKIV AAKYEVIHSK TKVNVKSVKR NTDVPESQQN FHRPVKVRKK QIDKEPKIQS CNSGVKSVKN QAHSVLKKTL QDQTLVQIFK PLTHSLSDKS HAHPGCLKEP HHPAQTGHVS HSSQKQCHKP QQQAPAMKTN SHVKEELEHP GVEHFKEEDK LKLKKPEKNL QPRQRRSSKS FSLDEPPLFI PDNIATIRRE GSDHSSSFES KYMWTPSKQC GFCKKPHGNR FMVGCGRCDD WFHGDCVGLS LSQAQQMGEE DKEYVCVKCC AEEDKKTEIL DPDTLENQAT VEFHSGDKTM ECEKLGLSKH TTNDRTKYID DTVKHKVKIL KRESGEGRNS SDCRDNEIKK WQLAPLRKMG QPVLPRRSSE EKSEKIPKES TTVTCTGEKA SKPGTHEKQE MKKKKVEKGV LNVHPAASAS KPSADQIRQS VRHSLKDILM KRLTDSNLKV PEEKAAKVAT KIEKELFSFF RDTDAKYKNK YRSLMFNLKD PKNNILFKKV LKGEVTPDHL IRMSPEELAS KELAAWRRRE NRHTIEMIEK EQREVERRPI TKITHKGEIE IESDAPMKEQ EAAMEIQEPA ANKSLEKPEG SEKQKEEVDS MSKDTTSQHR QHLFDLNCKI CIGRMAPPVD DLSPKKVKVV VGVARKHSDN EAESIADALS STSNILASEF FEEEKQESPK STFSPAPRPE MPGTVEVEST FLARLNFIWK GFINMPSVAK FVTKAYPVSG SPEYLTEDLP DSIQVGGRIS PQTVWDYVEK IKASGTKEIC VVRFTPVTEE DQISYTLLFA YFSSRKRYGV AANNMKQVKD MYLIPLGATD KIPHPLVPFD GPGLELHRPN LLLGLIIRQK LKRQHSACAS TSHIAETPES APPIALPPDK KSKIEVSTEE APEEENDFFN SFTTVLHKQR NKPQQNLQED LPTAVEPLME VTKQEPPKPL RFLPGVLIGW ENQPTTLELA NKPLPVDDIL QSLLGTTGQV YDQAQSVMEQ NTVKEIPFLN EQTNSKIEKT DNVEVTDGEN KEIKVKVDNI SESTDKSAEI ETSVVGSSSI SAGSLTSLSL RGKPPDVSTE AFLTNLSIQS KQEETVESKE KTLKRQLQED QENNLQDNQT SNSSPCRSNV GKGNIDGNVS CSENLVANTA RSPQFINLKR DPRQAAGRSQ PVTTSESKDG DSCRNGEKHM LPGLSHNKEH LTEQINVEEK LCSAEKNSCV QQSDNLKVAQ NSPSVENIQT SQAEQAKPLQ EDILMQNIET VHPFRRGSAV ATSHFEVGNT CPSEFPSKSI TFTSRSTSPR TSTNFSPMRP QQPNLQHLKS SPPGFPFPGP PNFPPQSMFG FPPHLPPPLL PPPGFGFAQN PMVPWPPVVH LPGQPQRMMG PLSQASRYIG PQNFYQVKDI RRPERRHSDP WGRQDQQQLD RPFNRGKGDR QRFYSDSHHL KRERHEKEWE QESERHRRRD RSQDKDRDRK SREEGHKDKE RARLSHGDRG TDGKASRDSR NVDKKPDKPK SEDYEKDKER EKSKHREGEK DRDRYHKDRD HTDRTKSKR
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