About Tetratricopeptide repeat protein 9A
Tetratricopeptide repeat protein 9A (TTC9) is a protein
from Homo sapiens identified by UniProt accession
Q92623, 222 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Tetratricopeptide repeat protein 9A |
|---|
| UniProt accession | Q92623 |
|---|
| Gene | TTC9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (45)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.30
- heel bone mineral density · score 0.30
- low density lipoprotein cholesterol measurement · score 0.26
- arterial stiffness measurement · score 0.24
- prostate carcinoma · score 0.23
- osteoarthritis, knee · score 0.21
- medical procedure · score 0.21
- lung adenocarcinoma · score 0.07
- neoplasm · score 0.05
- Sertoli Cell-Only Syndrome · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92623-F1 | alphafold | PREDICTED | 78.64 | — |
Amino-acid sequence (222 residues)
MERKGSAAGA KGNPSPPAAG EGQRPPPPLC VPGGGGGAPA RGQVGAAAEP AELIRRAHEF KSQGAQCYKD KKFREAIGKY HRALLELKGL LPPPGERERD SRPASPAGAL KPGRLSEEQS KTVEAIEIDC YNSLAACLLQ AELVNYERVK EYCLKVLKKE GENFKALYRS GVAFYHLGDY DKALYYLKEA RTQQPTDTNV IRYIQLTEMK LSRCSQREKE AM
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