About Uncharacterized protein KIAA0232
Uncharacterized protein KIAA0232 (KIAA0232) is a protein
from Homo sapiens identified by UniProt accession
Q92628, 1395 residues long.
MolForge cross-references it against 0 known binders and
37 disease associations.
Target properties
| Protein name | Uncharacterized protein KIAA0232 |
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| UniProt accession | Q92628 |
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| Gene | KIAA0232 |
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| Organism | Homo sapiens |
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| Length | 1395 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (37)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.30
- platelet count · score 0.29
- drug use measurement · score 0.26
- Red cell distribution width · score 0.20
- hemoglobin measurement · score 0.15
- lymphocyte count · score 0.11
- autism spectrum disorder · score 0.09
- neutrophil count · score 0.08
- mean corpuscular volume · score 0.08
- platelet component distribution width · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92628-F1 | alphafold | PREDICTED | 41.46 | — |
Amino-acid sequence (1395 residues)
MYPICTVVVD GLPSESSSSS YPGPVSVSEM SLLHALGPVQ TWLGQELEKC GIDAMIYTRY VLSLLLHDSY DYDLQEQEND IFLGWEKGAY KKWGKSKKKC SDLTLEEMKK QAAVQCLRSA SDESSGIETL VEELCSRLKD LQSKQEEKIH KKLEGSPSPE AELSPPAKDQ VEMYYEAFPP LSEKPVCLQE IMTVWNKSKV CSYSSSSSSS TAPPASTDTS SPKDCNSESE VTKERSSEVP TTVHEKTQSK SKNEKENKFS NGTIEEKPAL YKKQIRHKPE GKIRPRSWSS GSSEAGSSSS GNQGELKASM KYVKVRHKAR EIRNKKGRNG QSRLSLKHGE KAERNIHTGS SSSSSSGSVK QLCKRGKRPL KEIGRKDPGS TEGKDLYMEN RKDTEYKEEP LWYTEPIAEY FVPLSRKSKL ETTYRNRQDT SDLTSEAVEE LSESVHGLCI SNNNLHKTYL AAGTFIDGHF VEMPAVINED IDLTGTSLCS LPEDNKYLDD IHLSELTHFY EVDIDQSMLD PGASETMQGE SRILNMIRQK SKENTDFEAE CCIVLDGMEL QGERAIWTDS TSSVGAEGLF LQDLGNLAQF WECCSSSSGD ADGESFGGDS PVRLSPILDS TVLNSHLLAG NQELFSDINE GSGINSCFSV FEVQCSNSVL PFSFETLNLG NENTDSSANM LGKTQSRLLI WTKNSAFEEN EHCSNLSTRT CSPWSHSEET RSDNETLNIQ FEESTQFNAE DINYVVPRVS SNYVDEELLD FLQDETCQQN SRTLGEIPTL VFKKTSKLES VCGIQLEQKT ENKNFETTQV CNESPHGDGY SSGVIKDIWT KMADTNSVAT VEIERTDAEL FSADVNNYCC CLDAEAELET LQEPDKAVRR SEYHLWEGQK ESLEKRAFAS SELSNVDGGD YTTPSKPWDV AQDKENTFIL GGVYGELKTF NSDGEWAVVP PSHTKGSLLQ CAASDVVTIA GTDVFMTPGN SFAPGHRQLW KPFVSFEQND QPKSGENGLN KGFSFIFHED LLGACGNFQV EDPGLEYSFS SFDLSNPFSQ VLHVECSFEP EGIASFSPSF KPKSILCSDS DSEVFHPRIC GVDRTQYRAI RISPRTHFRP ISASELSPGG GSESEFESEK DEANIPIPSQ VDIFEDPQAD LKPLEEDAEK EGHYYGKSEL ESGKFLPRLK KSGMEKSAQT SLDSQEESTG ILSVGKQNQC LECSMNESLE IDLESSEANC KIMAQCEEEI NNFCGCKAGC QFPAYEDNPV SSGQLEEFPV LNTDIQGMNR SQEKQTWWEK ALYSPLFPAS ECEECYTNAK GESGLEEYPD AKETPSNEER LLDFNRVSSV YEARCTGERD SGAKSDGFRG KMCSSASSTS EETGSEGGGE WVGPSEEELF SRTHL
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