Small ribosomal subunit protein mS31 (MRPS31)

About Small ribosomal subunit protein mS31

Small ribosomal subunit protein mS31 (MRPS31) is a protein from Homo sapiens identified by UniProt accession Q92665, 395 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.

Target properties

Protein name	Small ribosomal subunit protein mS31
UniProt accession	Q92665
Gene	MRPS31
Organism	Homo sapiens
Length	395 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (65)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.47
mean corpuscular volume · score 0.37
mean corpuscular hemoglobin concentration · score 0.33
erythrocyte count · score 0.33
mean corpuscular hemoglobin · score 0.28
mean reticulocyte volume · score 0.28
body height · score 0.27
lean body mass · score 0.20
myeloproliferative disorder · score 0.20
basophil count · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92665-F1	alphafold	PREDICTED	66.12	—

Amino-acid sequence (395 residues)

MFPRVSTFLP LRPLSRHPLS SGSPETSAAA IMLLTVRHGT VRYRSSALLA RTKNNIQRYF GTNSVICSKK DKQSVRTEET SKETSESQDS EKENTKKDLL GIIKGMKVEL STVNVRTTKP PKRRPLKSLE ATLGRLRRAT EYAPKKRIEP LSPELVAAAS AVADSLPFDK QTTKSELLSQ LQQHEEESRA QRDAKRPKIS FSNIISDMKV ARSATARVRS RPELRIQFDE GYDNYPGQEK TDDLKKRKNI FTGKRLNIFD MMAVTKEAPE TDTSPSLWDV EFAKQLATVN EQPLQNGFEE LIQWTKEGKL WEFPINNEAG FDDDGSEFHE HIFLEKHLES FPKQGPIRHF MELVTCGLSK NPYLSVKQKV EHIEWFRNYF NEKKDILKES NIQFN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards