About Regulatory solute carrier protein family 1 member 1
Regulatory solute carrier protein family 1 member 1 (RSC1A1) is a protein
from Homo sapiens identified by UniProt accession
Q92681, 617 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Regulatory solute carrier protein family 1 member 1 |
|---|
| UniProt accession | Q92681 |
|---|
| Gene | RSC1A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 617 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.27
- chronotype measurement · score 0.15
- pulse pressure measurement · score 0.14
- serum urea measurement · score 0.14
- brain measurement · score 0.14
- obesity due to melanocortin 4 receptor deficiency · score 0.06
- Obesity · score 0.04
- obesity due to leptin receptor gene deficiency · score 0.04
- obesity · score 0.04
- obesity due to prohormone convertase I deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92681-F1 | alphafold | PREDICTED | 47.89 | — |
Amino-acid sequence (617 residues)
MSSLPTSDGF NHPARSSGQS PDVGNPMSLA RSVSASVCPI KPSDSDRIEP KAVKALKASA EFQLNSEKKE HLSLQDLSDH ASSADHAPTD QSPAMPMQNS SEEITVAGNL EKSAERSTQG LKFHLHTRQE ASLSVTSTRM HEPQMFLGEK DWHPENQNLS QVSDPQQHEE PGNEQYEVAQ QKASHDQEYL CNIGDLELPE ERQQNQHKIV DLEATMKGNG LPQNVDPPSA KKSIPSSECS GCSNSETFME IDTAQQSLVT LLNSTGRQNA NVKNIGALDL TLDNPLMEVE TSKCNPSSEI LNDSISTQDL QPPETNVEIP GTNKEYGHYS SPSLCGSCQP SVESAEESCP SITAALKELH ELLVVSSKPA SENTSEEVIC QSETIAEGQT SIKDLSERWT QNEHLTQNEQ CPQVSFHQAI SVSVETEKLT GTSSDTGREA VENVNFRSLG DGLSTDKEGV PKSRESINKN RSVTVTSAKT SNQLHCTLGV EISPKLLAGE EDALNQTSEQ TKSLSSNFIL VKDLGQGIQN SVTDRPETRE NVCPDASRPL LEYEPPTSHP SSSPAILPPL IFPATDIDRI LRAGFTLQEA LGALHRVGGN ADLALLVLLA KNIVVPT
Explore Regulatory solute carrier protein family 1 member 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets