About Ras-like protein family member 10A
Ras-like protein family member 10A (RASL10A) is a protein
from Homo sapiens identified by UniProt accession
Q92737, 203 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Ras-like protein family member 10A |
|---|
| UniProt accession | Q92737 |
|---|
| Gene | RASL10A |
|---|
| Organism | Homo sapiens |
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| Length | 203 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.20
- platelet component distribution width · score 0.13
- Immature Reticulocyte Fraction Measurement · score 0.11
- heel bone mineral density · score 0.09
- platelet count · score 0.08
- lymphocyte count · score 0.07
- aspartate aminotransferase measurement · score 0.05
- reticulocyte measurement · score 0.05
- reticulocyte count · score 0.04
- glioblastoma multiforme · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92737-F1 | alphafold | PREDICTED | 80.72 | — |
Amino-acid sequence (203 residues)
MGGSLRVAVL GAPGVGKTAI IRQFLFGDYP ERHRPTDGPR LYRPAVLLDG AVYDLSIRDG DVAGPGSSPG GPEEWPDAKD WSLQDTDAFV LVYDICSPDS FDYVKALRQR IAETRPAGAP EAPILVVGNK RDRQRLRFGP RRALAALVRR GWRCGYLECS AKYNWHVLRL FRELLRCALV RARPAHPALR LQGALHPARC SLM
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