Zinc finger protein neuro-d4 (DPF1)

About Zinc finger protein neuro-d4

Zinc finger protein neuro-d4 (DPF1) is a protein from Homo sapiens identified by UniProt accession Q92782, 387 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Zinc finger protein neuro-d4
UniProt accession	Q92782
Gene	DPF1
Organism	Homo sapiens
Length	387 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.48
serum gamma-glutamyl transferase measurement · score 0.13
platelet crit · score 0.13
monocyte count · score 0.05
appendicular lean mass · score 0.05
mathematical ability · score 0.04
attention deficit hyperactivity disorder · score 0.04
brain measurement · score 0.04
schizophrenia 15 · score 0.04
breast carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92782-F1	alphafold	PREDICTED	67.51	—

Amino-acid sequence (387 residues)

MATVIPGPLS LGEDFYREAI EHCRSYNARL CAERSLRLPF LDSQTGVAQN NCYIWMEKTH RGPGLAPGQI YTYPARCWRK KRRLNILEDP RLRPCEYKID CEAPLKKEGG LPEGPVLEAL LCAETGEKKI ELKEEETIMD CQKQQLLEFP HDLEVEDLED DIPRRKNRAK GKAYGIGGLR KRQDTASLED RDKPYVCDIC GKRYKNRPGL SYHYTHTHLA EEEGEENAER HALPFHRKNN HKQFYKELAW VPEAQRKHTA KKAPDGTVIP NGYCDFCLGG SKKTGCPEDL ISCADCGRSG HPSCLQFTVN MTAAVRTYRW QCIECKSCSL CGTSENDDQL LFCDDCDRGY HMYCLSPPMA EPPEGSWSCH LCLRHLKEKA SAYITLT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards