Zinc finger protein DPF3 (DPF3)

About Zinc finger protein DPF3

Zinc finger protein DPF3 (DPF3) is a protein from Homo sapiens identified by UniProt accession Q92784, 378 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.

Target properties

Protein name	Zinc finger protein DPF3
UniProt accession	Q92784
Gene	DPF3
Organism	Homo sapiens
Length	378 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (86)

Diseases linked to this target (Open Targets).

body mass index · score 0.48
sex hormone-binding globulin measurement · score 0.46
urate measurement · score 0.45
hematocrit · score 0.45
C-reactive protein measurement · score 0.44
renal cell carcinoma · score 0.44
creatinine measurement · score 0.41
neurodegenerative disease · score 0.40
heart rate response to recovery post exercise · score 0.39
IGF-1 measurement · score 0.39

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92784-F1	alphafold	PREDICTED	73.44	—

Amino-acid sequence (378 residues)

MATVIHNPLK ALGDQFYKEA IEHCRSYNSR LCAERSVRLP FLDSQTGVAQ NNCYIWMEKR HRGPGLAPGQ LYTYPARCWR KKRRLHPPED PKLRLLEIKP EVELPLKKDG FTSESTTLEA LLRGEGVEKK VDAREEESIQ EIQRVLENDE NVEEGNEEED LEEDIPKRKN RTRGRARGSA GGRRRHDAAS QEDHDKPYVC DICGKRYKNR PGLSYHYAHT HLASEEGDEA QDQETRSPPN HRNENHRPQK GPDGTVIPNN YCDFCLGGSN MNKKSGRPEE LVSCADCGRS GHPTCLQFTL NMTEAVKTYK WQCIECKSCI LCGTSENDDQ LLFCDDCDRG YHMYCLNPPV AEPPEGSWSC HLCWELLKEK ASAFGCQA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards