Zinc finger protein ubi-d4 (DPF2)

About Zinc finger protein ubi-d4

Zinc finger protein ubi-d4 (DPF2) is a protein from Homo sapiens identified by UniProt accession Q92785, 391 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	Zinc finger protein ubi-d4
UniProt accession	Q92785
Gene	DPF2
Organism	Homo sapiens
Length	391 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

Coffin-Siris syndrome · score 0.71
neurodegenerative disease · score 0.55
genetic disorder · score 0.46
Intellectual disability · score 0.37
lysosomal storage disease · score 0.37
mean corpuscular hemoglobin concentration · score 0.13
urate measurement · score 0.12
body height · score 0.07
mean corpuscular volume · score 0.05
basophil count · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92785-F1	alphafold	PREDICTED	69.45	—

Amino-acid sequence (391 residues)

MAAVVENVVK LLGEQYYKDA MEQCHNYNAR LCAERSVRLP FLDSQTGVAQ SNCYIWMEKR HRGPGLASGQ LYSYPARRWR KKRRAHPPED PRLSFPSIKP DTDQTLKKEG LISQDGSSLE ALLRTDPLEK RGAPDPRVDD DSLGEFPVTN SRARKRILEP DDFLDDLDDE DYEEDTPKRR GKGKSKGKGV GSARKKLDAS ILEDRDKPYA CDICGKRYKN RPGLSYHYAH SHLAEEEGED KEDSQPPTPV SQRSEEQKSK KGPDGLALPN NYCDFCLGDS KINKKTGQPE ELVSCSDCGR SGHPSCLQFT PVMMAAVKTY RWQCIECKCC NICGTSENDD QLLFCDDCDR GYHMYCLTPS MSEPPEGSWS CHLCLDLLKE KASIYQNQNS S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards