About NEDD4-binding protein 2-like 2
NEDD4-binding protein 2-like 2 (N4BP2L2) is a protein
from Homo sapiens identified by UniProt accession
Q92802, 583 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | NEDD4-binding protein 2-like 2 |
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| UniProt accession | Q92802 |
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| Gene | N4BP2L2 |
|---|
| Organism | Homo sapiens |
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| Length | 583 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (55)
Diseases linked to this target (Open Targets).
- Short stature · score 0.33
- neurodegenerative disease · score 0.27
- mean corpuscular volume · score 0.25
- platelet count · score 0.25
- mean reticulocyte volume · score 0.24
- body height · score 0.22
- low density lipoprotein cholesterol measurement · score 0.22
- coronary artery disease · score 0.22
- creatinine measurement · score 0.22
- myocardial infarction · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92802-F1 | alphafold | PREDICTED | 54.81 | — |
Amino-acid sequence (583 residues)
MSYGEIEGKF LGPREEVTSE PRCKKLKSTT ESYVFHNHSN ADFHRIQEKT GNDWVPVTII DVRGHSYLQE NKIKTTDLHR PLHDEMPGNR PDVIESIDSQ VLQEARPPLV SADDEIYSTS KAFIGPIYKP PEKKKRNEGR NEAHVLNGIN DRGGQKEKQK FNSEKSEIDN ELFQFYKEIE ELEKEKDGFE NSCKESEPSQ EQFVPFYEGH NNGLLKPDEE KKDLSNKAMP SHCDYQQNLG NEPDKYPCNG QVIPTFCDTS FTSFRPEWQS VYPFIVPYGP PLPSLNYHLN IQRFSGPPNP PSNIFQAQDD SQIQNGYYVN NCHVNWNCMT FDQNNEYTDC SENRSSVHPS GNGCSMQDRY VSNGFCEVRE RCWKDHCMDK HNGTDRFVNQ QFQEEKLNKL QKLLILLRGL PGSGKTTLSR ILLGQNRDGI VFSTDDYFHH QDGYRYNVNQ LGDAHDWNQN RAKQAIDQGR SPVIIDNTNI QAWEMKPYVE VAIGKGYRVE FHEPETWWKF DPEELEKRNK HGVSRKKIAQ MLDRYEYQMS ISIVMNSVEP SHKSTQRPPP PQGRQRWGGS LGSHNRVCVT NNH
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