About Homeobox protein Hox-B13
Homeobox protein Hox-B13 (HOXB13) is a protein
from Homo sapiens identified by UniProt accession
Q92826, 284 residues long.
MolForge cross-references it against 0 known binders and
131 disease associations.
Target properties
| Protein name | Homeobox protein Hox-B13 |
|---|
| UniProt accession | Q92826 |
|---|
| Gene | HOXB13 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 284 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (131)
Diseases linked to this target (Open Targets).
- Familial prostate cancer · score 0.53
- gastric cancer · score 0.50
- prostate carcinoma · score 0.49
- familial prostate carcinoma · score 0.45
- prostate adenocarcinoma · score 0.37
- hereditary neoplastic syndrome · score 0.35
- Inherited cancer-predisposing syndrome · score 0.35
- prostate cancer · score 0.31
- systolic blood pressure · score 0.29
- cancer · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92826-F1 | alphafold | PREDICTED | 61.04 | — |
Amino-acid sequence (284 residues)
MEPGNYATLD GAKDIEGLLG AGGGRNLVAH SPLTSHPAAP TLMPAVNYAP LDLPGSAEPP KQCHPCPGVP QGTSPAPVPY GYFGGGYYSC RVSRSSLKPC AQAATLAAYP AETPTAGEEY PSRPTEFAFY PGYPGTYQPM ASYLDVSVVQ TLGAPGEPRH DSLLPVDSYQ SWALAGGWNS QMCCQGEQNP PGPFWKAAFA DSSGQHPPDA CAFRRGRKKR IPYSKGQLRE LEREYAANKF ITKDKRRKIS AATSLSERQI TIWFQNRRVK EKKVLAKVKN SATP
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