Coronin-2A (CORO2A)

About Coronin-2A

Coronin-2A (CORO2A) is a protein from Homo sapiens identified by UniProt accession Q92828, 525 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.

Target properties

Protein name	Coronin-2A
UniProt accession	Q92828
Gene	CORO2A
Organism	Homo sapiens
Length	525 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (43)

Diseases linked to this target (Open Targets).

myoepithelial tumor · score 0.11
bone density · score 0.10
urate measurement · score 0.10
oral squamous cell carcinoma · score 0.07
multiple sclerosis · score 0.05
smoking status measurement · score 0.04
adolescent idiopathic scoliosis · score 0.04
body height · score 0.03
childhood trauma measurement · score 0.03
alcohol consumption measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q92828-F1	alphafold	PREDICTED	85.39	—

Amino-acid sequence (525 residues)

MSWHPQYRSS KFRHVFGKPA SKENCYDSVP ITRSVHDNHF CAVNPHFIAV VTECAGGGAF LVIPLHQTGK LDPHYPKVCG HRGNVLDVKW NPFDDFEIAS CSEDATIKIW SIPKQLLTRN LTAYRKELVG HARRVGLVEW HPTAANILFS AGYDYKVMIW NLDTKESVIT SPMSTISCHQ DVILSMSFNT NGSLLATTCK DRKIRVIDPR AGTVLQEASY KGHRASKVLF LGNLKKLMST GTSRWNNRQV ALWDQDNLSV PLMEEDLDGS SGVLFPFYDA DTSMLYVVGK GDGNIRYYEV SADKPHLSYL TEYRSYNPQK GIGVMPKRGL DVSSCEIFRF YKLITTKSLI EPISMIVPRR SESYQEDIYP PTAGAQPSLT AQEWLSGMNR DPILVSLRPG SELLRPHPLP AERPIFNSMA PASPRLLNQT EKLAAEDGWR SSSLLEEKMP RWAAEHRLEE KKTWLTNGFD VFECPPPKTE NELLQMFYRQ QEEIRRLREL LTQREVQAKQ LELEIKNLRM GSEQL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards