About Osteoclast-stimulating factor 1
Osteoclast-stimulating factor 1 (OSTF1) is a protein
from Homo sapiens identified by UniProt accession
Q92882, 214 residues long.
MolForge cross-references it against 0 known binders and
98 disease associations.
Target properties
| Protein name | Osteoclast-stimulating factor 1 |
|---|
| UniProt accession | Q92882 |
|---|
| Gene | OSTF1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 214 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (98)
Diseases linked to this target (Open Targets).
- basophil count · score 0.25
- loneliness measurement · score 0.23
- adolescent idiopathic scoliosis · score 0.21
- metabolite measurement · score 0.18
- neoplasm · score 0.09
- age-related macular degeneration · score 0.07
- X-linked retinal dysplasia · score 0.07
- Familial exudative vitreoretinopathy · score 0.07
- Gorham-Stout disease · score 0.07
- melorheostosis · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92882-F1 | alphafold | PREDICTED | 90.21 | — |
Amino-acid sequence (214 residues)
MSKPPPKPVK PGQVKVFRAL YTFEPRTPDE LYFEEGDIIY ITDMSDTNWW KGTSKGRTGL IPSNYVAEQA ESIDNPLHEA AKRGNLSWLR ECLDNRVGVN GLDKAGSTAL YWACHGGHKD IVEMLFTQPN IELNQQNKLG DTALHAAAWK GYADIVQLLL AKGARTDLRN IEKKLAFDMA TNAACASLLK KKQGTDAVRT LSNAEDYLDD EDSD
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