About Neurogenin-1
Neurogenin-1 (NEUROG1) is a protein
from Homo sapiens identified by UniProt accession
Q92886, 237 residues long.
MolForge cross-references it against 0 known binders and
89 disease associations.
Target properties
| Protein name | Neurogenin-1 |
|---|
| UniProt accession | Q92886 |
|---|
| Gene | NEUROG1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 237 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (89)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- Worster-Drought syndrome · score 0.04
- Charcot-Marie-Tooth disease type 4E · score 0.04
- Hypomyelination neuropathy - arthrogryposis · score 0.03
- adenoma · score 0.03
- schizophrenia · score 0.03
- neoplasm · score 0.02
- Autism · score 0.02
- Stroke · score 0.01
- carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q92886-F1 | alphafold | PREDICTED | 65.08 | — |
Amino-acid sequence (237 residues)
MPARLETCIS DLDCASSSGS DLSGFLTDEE DCARLQQAAS ASGPPAPARR GAPNISRASE VPGAQDDEQE RRRRRGRTRV RSEALLHSLR RSRRVKANDR ERNRMHNLNA ALDALRSVLP SFPDDTKLTK IETLRFAYNY IWALAETLRL ADQGLPGGGA RERLLPPQCV PCLPGPPSPA SDAESWGSGA AAASPLSDPS SPAASEDFTY RPGDPVFSFP SLPKDLLHTT PCFIPYH
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